Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis

Extracellular vesicles (EVs), including exosomes and microvesicles, are evolutionarily conserved phospholidpid membrane-bound entities secreted from most eukaryotic cell types. They carry bioactive cargos such as protein and nucleic acids derived from their cells of origin. Over the past 10 years, t...

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Detalles Bibliográficos
Autores principales: Zhao, Mengmeng, Nanbo, Asuka, Sun, Lichun, Lin, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406486/
https://www.ncbi.nlm.nih.gov/pubmed/30754656
http://dx.doi.org/10.3390/microorganisms7020048
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author Zhao, Mengmeng
Nanbo, Asuka
Sun, Lichun
Lin, Zhen
author_facet Zhao, Mengmeng
Nanbo, Asuka
Sun, Lichun
Lin, Zhen
author_sort Zhao, Mengmeng
collection PubMed
description Extracellular vesicles (EVs), including exosomes and microvesicles, are evolutionarily conserved phospholidpid membrane-bound entities secreted from most eukaryotic cell types. They carry bioactive cargos such as protein and nucleic acids derived from their cells of origin. Over the past 10 years, they have been attracting increased attention in many fields of life science, representing a new route for intercellular communication. In this review article, we will discuss the current knowledge of both normal and virally modified EVs in the regulation of Epstein-Barr virus (EBV)’s life cycle and its associated pathogenesis.
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spelling pubmed-64064862019-03-26 Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis Zhao, Mengmeng Nanbo, Asuka Sun, Lichun Lin, Zhen Microorganisms Review Extracellular vesicles (EVs), including exosomes and microvesicles, are evolutionarily conserved phospholidpid membrane-bound entities secreted from most eukaryotic cell types. They carry bioactive cargos such as protein and nucleic acids derived from their cells of origin. Over the past 10 years, they have been attracting increased attention in many fields of life science, representing a new route for intercellular communication. In this review article, we will discuss the current knowledge of both normal and virally modified EVs in the regulation of Epstein-Barr virus (EBV)’s life cycle and its associated pathogenesis. MDPI 2019-02-11 /pmc/articles/PMC6406486/ /pubmed/30754656 http://dx.doi.org/10.3390/microorganisms7020048 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhao, Mengmeng
Nanbo, Asuka
Sun, Lichun
Lin, Zhen
Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis
title Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis
title_full Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis
title_fullStr Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis
title_full_unstemmed Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis
title_short Extracellular Vesicles in Epstein-Barr Virus’ Life Cycle and Pathogenesis
title_sort extracellular vesicles in epstein-barr virus’ life cycle and pathogenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406486/
https://www.ncbi.nlm.nih.gov/pubmed/30754656
http://dx.doi.org/10.3390/microorganisms7020048
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AT nanboasuka extracellularvesiclesinepsteinbarrviruslifecycleandpathogenesis
AT sunlichun extracellularvesiclesinepsteinbarrviruslifecycleandpathogenesis
AT linzhen extracellularvesiclesinepsteinbarrviruslifecycleandpathogenesis

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