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Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms

Tortuosity of blood vessels is a common angiographic finding that may indicate systemic disease and can be correlated with vascular pathologies. In this work, we determined whether patients with and without internal carotid artery (ICA) aneurysm presented with differences in its tortuosity descripto...

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Autores principales: Kliś, Kornelia M., Krzyżewski, Roger M., Kwinta, Borys M., Stachura, Krzysztof, Gąsowski, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406528/
https://www.ncbi.nlm.nih.gov/pubmed/30759737
http://dx.doi.org/10.3390/jcm8020237
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author Kliś, Kornelia M.
Krzyżewski, Roger M.
Kwinta, Borys M.
Stachura, Krzysztof
Gąsowski, Jerzy
author_facet Kliś, Kornelia M.
Krzyżewski, Roger M.
Kwinta, Borys M.
Stachura, Krzysztof
Gąsowski, Jerzy
author_sort Kliś, Kornelia M.
collection PubMed
description Tortuosity of blood vessels is a common angiographic finding that may indicate systemic disease and can be correlated with vascular pathologies. In this work, we determined whether patients with and without internal carotid artery (ICA) aneurysm presented with differences in its tortuosity descriptors. We retrospectively analysed data of 298 patients hospitalized between January 2014 and June 2018. For each patient’s imaging data, we extracted a curve representing the ICA course and measured its Relative Length (RL), Sum of Angle Metrics (SOAM), Product of Angle Distance (PAD), Triangular Index (TI), and Inflection Count Metrics (ICM). We found that patients with an ICA aneurysm had significantly lower RL (0.46 ± 0.19 vs. 0.51 ± 0.17; p = 0.023) and significantly higher SOAM (0.39 ± 0.21 vs. 0.32 ± 0.21 p = 0.003), PAD (0.38 ± 0.19 vs. 0.32 ± 0.21; p = 0.011), TI (0.30 ± 0.11 vs. 0.27 ± 0.14; p = 0.034), and ICM (0.30 ± 0.16 vs. 0.22 ± 0.12; p < 0.001). We found that that patients who presented with a subarachnoid hemorrhage had significantly higher PAD (0.46 ± 0.22 vs. 0.35 ± 0.20; p = 0.024). In conclusion, higher tortuosity of ICA is associated with ICA aneurysm presence.
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spelling pubmed-64065282019-03-22 Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms Kliś, Kornelia M. Krzyżewski, Roger M. Kwinta, Borys M. Stachura, Krzysztof Gąsowski, Jerzy J Clin Med Article Tortuosity of blood vessels is a common angiographic finding that may indicate systemic disease and can be correlated with vascular pathologies. In this work, we determined whether patients with and without internal carotid artery (ICA) aneurysm presented with differences in its tortuosity descriptors. We retrospectively analysed data of 298 patients hospitalized between January 2014 and June 2018. For each patient’s imaging data, we extracted a curve representing the ICA course and measured its Relative Length (RL), Sum of Angle Metrics (SOAM), Product of Angle Distance (PAD), Triangular Index (TI), and Inflection Count Metrics (ICM). We found that patients with an ICA aneurysm had significantly lower RL (0.46 ± 0.19 vs. 0.51 ± 0.17; p = 0.023) and significantly higher SOAM (0.39 ± 0.21 vs. 0.32 ± 0.21 p = 0.003), PAD (0.38 ± 0.19 vs. 0.32 ± 0.21; p = 0.011), TI (0.30 ± 0.11 vs. 0.27 ± 0.14; p = 0.034), and ICM (0.30 ± 0.16 vs. 0.22 ± 0.12; p < 0.001). We found that that patients who presented with a subarachnoid hemorrhage had significantly higher PAD (0.46 ± 0.22 vs. 0.35 ± 0.20; p = 0.024). In conclusion, higher tortuosity of ICA is associated with ICA aneurysm presence. MDPI 2019-02-12 /pmc/articles/PMC6406528/ /pubmed/30759737 http://dx.doi.org/10.3390/jcm8020237 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kliś, Kornelia M.
Krzyżewski, Roger M.
Kwinta, Borys M.
Stachura, Krzysztof
Gąsowski, Jerzy
Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms
title Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms
title_full Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms
title_fullStr Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms
title_full_unstemmed Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms
title_short Tortuosity of the Internal Carotid Artery and Its Clinical Significance in the Development of Aneurysms
title_sort tortuosity of the internal carotid artery and its clinical significance in the development of aneurysms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406528/
https://www.ncbi.nlm.nih.gov/pubmed/30759737
http://dx.doi.org/10.3390/jcm8020237
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