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A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness

Excess iron causes cancer and is thought to be related to carcinogenesis and cancer progression including stemness, but the details remain unclear. Here, we hypothesized that stemness in cancer is related to iron metabolism and that regulating iron metabolism in cancer stem cells (CSCs) may be a nov...

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Detalles Bibliográficos
Autores principales: Katsura, Yuki, Ohara, Toshiaki, Noma, Kazuhiro, Ninomiya, Takayuki, Kashima, Hajime, Kato, Takuya, Sato, Hiroaki, Komoto, Satoshi, Narusaka, Toru, Tomono, Yasuko, Xing, Boyi, Chen, Yuehua, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kasai, Tomonari, Seno, Masaharu, Matsukawa, Akihiro, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406536/
https://www.ncbi.nlm.nih.gov/pubmed/30717462
http://dx.doi.org/10.3390/cancers11020177