PI3k and Stat3: Oncogenes that are Required for Gap Junctional, Intercellular Communication

Gap junctional, intercellular communication (GJIC) is interrupted in cells transformed by oncogenes such as activated Src. The Src effector, Ras, is required for this effect, so that Ras inhibition restores GJIC in Src-transformed cells. Interestingly, the inhibition of the Src effector phosphatidyl...

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Detalles Bibliográficos
Autores principales: Geletu, Mulu, Taha, Zaid, Gunning, Patrick T., Raptis, Leda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406562/
https://www.ncbi.nlm.nih.gov/pubmed/30717267
http://dx.doi.org/10.3390/cancers11020167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406562/
https://www.ncbi.nlm.nih.gov/pubmed/30717267
http://dx.doi.org/10.3390/cancers11020167

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