A cell-based high-throughput screen identifies tyrphostin AG 879 as an inhibitor of animal cell phospholipid and fatty acid biosynthesis

Inhibition of animal cell phospholipid biosynthesis has been proposed for anticancer and antiviral therapies. Using CHO—K1 derived cell lines, we have developed and used a cell-based high-throughput procedure to screen a 1280 compound, small molecule library for inhibitors of phospholipid biosynthes...

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Detalles Bibliográficos
Autores principales: Zoeller, Raphael A., Geoghegan-Barek, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406593/
https://www.ncbi.nlm.nih.gov/pubmed/30899803
http://dx.doi.org/10.1016/j.bbrep.2019.100621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406593/
https://www.ncbi.nlm.nih.gov/pubmed/30899803
http://dx.doi.org/10.1016/j.bbrep.2019.100621

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