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Anti-Invasion and Antiangiogenic Effects of Stellettin B through Inhibition of the Akt/Girdin Signaling Pathway and VEGF in Glioblastoma Cells

Angiogenesis and invasion are highly related with tumor metastatic potential and recurrence prediction in the most aggressive brain cancer, glioblastoma multiforme (GBM). For the first time, this study reveals that marine-sponge-derived stellettin B reduces angiogenesis and invasion. We discovered t...

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Detalles Bibliográficos
Autores principales: Cheng, Shu-Yu, Chen, Nan-Fu, Lin, Pi-Yu, Su, Jui-Hsin, Chen, Bing-Hung, Kuo, Hsiao-Mei, Sung, Chun-Sung, Sung, Ping-Jyun, Wen, Zhi-Hong, Chen, Wu-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406657/
https://www.ncbi.nlm.nih.gov/pubmed/30769863
http://dx.doi.org/10.3390/cancers11020220