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An Integrative Systems Biology and Experimental Approach Identifies Convergence of Epithelial Plasticity, Metabolism, and Autophagy to Promote Chemoresistance

The evolution of therapeutic resistance is a major cause of death for cancer patients. The development of therapy resistance is shaped by the ecological dynamics within the tumor microenvironment and the selective pressure of the host immune system. These selective forces often lead to evolutionary...

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Detalles Bibliográficos
Autores principales:	Xu, Shengnan, Ware, Kathryn E., Ding, Yuantong, Kim, So Young, Sheth, Maya U., Rao, Sneha, Chan, Wesley, Armstrong, Andrew J., Eward, William C., Jolly, Mohit Kumar, Somarelli, Jason A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406733/ https://www.ncbi.nlm.nih.gov/pubmed/30736412 http://dx.doi.org/10.3390/jcm8020205

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