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Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam
Comorbidities are common in respiratory disease patients and have been well-known to impact their quality of life. The objective of this study is to estimate the minimal clinically important difference (MCID) of the health-related quality of life (HRQOL) among respiratory disease patients with diffe...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406871/ https://www.ncbi.nlm.nih.gov/pubmed/30736474 http://dx.doi.org/10.3390/jcm8020214 |
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author | Ngo, Chau Quy Phan, Phuong Thu Vu, Giap Van Pham, Quyen Le Thi Nguyen, Long Hoang Vu, Giang Thu Tran, Tung Thanh Nguyen, Huong Lan Thi Tran, Bach Xuan Latkin, Carl A. Ho, Cyrus S. H. Ho, Roger C. M. |
author_facet | Ngo, Chau Quy Phan, Phuong Thu Vu, Giap Van Pham, Quyen Le Thi Nguyen, Long Hoang Vu, Giang Thu Tran, Tung Thanh Nguyen, Huong Lan Thi Tran, Bach Xuan Latkin, Carl A. Ho, Cyrus S. H. Ho, Roger C. M. |
author_sort | Ngo, Chau Quy |
collection | PubMed |
description | Comorbidities are common in respiratory disease patients and have been well-known to impact their quality of life. The objective of this study is to estimate the minimal clinically important difference (MCID) of the health-related quality of life (HRQOL) among respiratory disease patients with different comorbidities in a Vietnamese tertiary hospital. We performed a cross-sectional study from October to November 2016 at the Respiratory Center of Bach Mai Hospital, Hanoi, with a total of 508 participants. Information about socio-economic characteristics, HRQOL and comorbidities of participants was collected. ANOVA was used to identify MCID between patients with and without specific comorbid conditions. Tobit regression was used to explore the associations between comorbidities and the HRQOL. Results showed that the prevalence of cardiovascular comorbidities was 23.8%, followed by musculoskeletal diseases (12.0%), digestive diseases (11.8%), endocrine diseases (10.0%), kidney diseases (5.1%) and ear, nose, and throat diseases (4.5%). Regarding HRQOL, having a problem in pain/discomfort was observed in 61.0% of participants, followed by anxiety/depression (48.2%). Mean EQ-5D index was 0.66 (SD (Standard Deviation) = 0.31). The significant MCID (p < 0.05) was found between patients with and without cardiovascular diseases, musculoskeletal diseases, kidney diseases, and endocrine diseases. The multivariate regression model showed that only musculoskeletal diseases were found to be related with the marked decrement of EQ-5D index score (Coef. = −0.13; 95% CI (Confident Interval) = −0.23; −0.02). Suffering at least one chronic illness was correlated to the marked decrease of EQ-5D index score (Coef. = −0.09; 95% CI = −0.17; −0.01). These results underline the importance of appropriate pain management as well as the provision of an interprofessional care approach to patients in order to alleviate the burden of comorbidities to their treatment outcomes and HRQOL. |
format | Online Article Text |
id | pubmed-6406871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64068712019-03-22 Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam Ngo, Chau Quy Phan, Phuong Thu Vu, Giap Van Pham, Quyen Le Thi Nguyen, Long Hoang Vu, Giang Thu Tran, Tung Thanh Nguyen, Huong Lan Thi Tran, Bach Xuan Latkin, Carl A. Ho, Cyrus S. H. Ho, Roger C. M. J Clin Med Article Comorbidities are common in respiratory disease patients and have been well-known to impact their quality of life. The objective of this study is to estimate the minimal clinically important difference (MCID) of the health-related quality of life (HRQOL) among respiratory disease patients with different comorbidities in a Vietnamese tertiary hospital. We performed a cross-sectional study from October to November 2016 at the Respiratory Center of Bach Mai Hospital, Hanoi, with a total of 508 participants. Information about socio-economic characteristics, HRQOL and comorbidities of participants was collected. ANOVA was used to identify MCID between patients with and without specific comorbid conditions. Tobit regression was used to explore the associations between comorbidities and the HRQOL. Results showed that the prevalence of cardiovascular comorbidities was 23.8%, followed by musculoskeletal diseases (12.0%), digestive diseases (11.8%), endocrine diseases (10.0%), kidney diseases (5.1%) and ear, nose, and throat diseases (4.5%). Regarding HRQOL, having a problem in pain/discomfort was observed in 61.0% of participants, followed by anxiety/depression (48.2%). Mean EQ-5D index was 0.66 (SD (Standard Deviation) = 0.31). The significant MCID (p < 0.05) was found between patients with and without cardiovascular diseases, musculoskeletal diseases, kidney diseases, and endocrine diseases. The multivariate regression model showed that only musculoskeletal diseases were found to be related with the marked decrement of EQ-5D index score (Coef. = −0.13; 95% CI (Confident Interval) = −0.23; −0.02). Suffering at least one chronic illness was correlated to the marked decrease of EQ-5D index score (Coef. = −0.09; 95% CI = −0.17; −0.01). These results underline the importance of appropriate pain management as well as the provision of an interprofessional care approach to patients in order to alleviate the burden of comorbidities to their treatment outcomes and HRQOL. MDPI 2019-02-07 /pmc/articles/PMC6406871/ /pubmed/30736474 http://dx.doi.org/10.3390/jcm8020214 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ngo, Chau Quy Phan, Phuong Thu Vu, Giap Van Pham, Quyen Le Thi Nguyen, Long Hoang Vu, Giang Thu Tran, Tung Thanh Nguyen, Huong Lan Thi Tran, Bach Xuan Latkin, Carl A. Ho, Cyrus S. H. Ho, Roger C. M. Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam |
title | Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam |
title_full | Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam |
title_fullStr | Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam |
title_full_unstemmed | Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam |
title_short | Effects of Different Comorbidities on Health-Related Quality of Life among Respiratory Patients in Vietnam |
title_sort | effects of different comorbidities on health-related quality of life among respiratory patients in vietnam |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406871/ https://www.ncbi.nlm.nih.gov/pubmed/30736474 http://dx.doi.org/10.3390/jcm8020214 |
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