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In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes

Of the hepatic cell lines developed for in vitro studies of hepatic functions as alternatives to primary human hepatocytes, many have lost major liver-like functions, but not HepaRG cells. The increasing use of the latter worldwide raises the need for establishing the reference functional status of...

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Detalles Bibliográficos
Autores principales: Tascher, Georg, Burban, Audrey, Camus, Sandrine, Plumel, Marine, Chanon, Stéphanie, Le Guevel, Remy, Shevchenko, Valery, Van Dorsselaer, Alain, Lefai, Etienne, Guguen-Guillouzo, Christiane, Bertile, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406872/
https://www.ncbi.nlm.nih.gov/pubmed/30795634
http://dx.doi.org/10.3390/cells8020192