A H2AX–CARP-1 Interaction Regulates Apoptosis Signaling Following DNA Damage

Cell Cycle and Apoptosis Regulatory Protein (CARP-1/CCAR1) is a peri-nuclear phosphoprotein that regulates apoptosis via chemotherapeutic Adriamycin (doxorubicin) and a novel class of CARP-1 functional mimetic (CFM) compounds. Although Adriamycin causes DNA damage, data from Comet assays revealed th...

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Detalles Bibliográficos
Autores principales: Sekhar, Sreeja C., Venkatesh, Jaganathan, Cheriyan, Vino T., Muthu, Magesh, Levi, Edi, Assad, Hadeel, Meister, Paul, Undyala, Vishnu V., Gauld, James W., Rishi, Arun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406907/
https://www.ncbi.nlm.nih.gov/pubmed/30769864
http://dx.doi.org/10.3390/cancers11020221

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