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Machine Learning Identifies Chemical Characteristics That Promote Enzyme Catalysis

[Image: see text] Despite tremendous progress in understanding and engineering enzymes, knowledge of how enzyme structures and their dynamics induce observed catalytic properties is incomplete, and capabilities to engineer enzymes fall far short of industrial needs. Here, we investigate the structur...

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Detalles Bibliográficos
Autores principales: Bonk, Brian M., Weis, James W., Tidor, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407039/
https://www.ncbi.nlm.nih.gov/pubmed/30761897
http://dx.doi.org/10.1021/jacs.8b13879