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Machine Learning Identifies Chemical Characteristics That Promote Enzyme Catalysis
[Image: see text] Despite tremendous progress in understanding and engineering enzymes, knowledge of how enzyme structures and their dynamics induce observed catalytic properties is incomplete, and capabilities to engineer enzymes fall far short of industrial needs. Here, we investigate the structur...
Autores principales: | Bonk, Brian M., Weis, James W., Tidor, Bruce |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407039/ https://www.ncbi.nlm.nih.gov/pubmed/30761897 http://dx.doi.org/10.1021/jacs.8b13879 |
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