Cargando…

Decoration of Anti-CD38 on Nanoparticles Carrying a STAT3 Inhibitor Can Improve the Therapeutic Efficacy Against Myeloma

STAT3 is an oncoprotein which has been shown to contribute to drug resistance in multiple myeloma (MM). Nonetheless, the clinical utility of STAT3 inhibitors in treating MM has been limited, partly related to some of their pharmacologic properties. To overcome these challenges, our group had previou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yung-Hsing, Vakili, Mohammad Reza, Molavi, Ommoleila, Morrissey, Yuen, Wu, Chengsheng, Paiva, Igor, Soleimani, Amir Hasan, Sanaee, Forugh, Lavasanifar, Afsaneh, Lai, Raymond
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407065/ https://www.ncbi.nlm.nih.gov/pubmed/30791634 http://dx.doi.org/10.3390/cancers11020248

Ejemplares similares

Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model
por: Huang, Yung-Hsing, et al.
Publicado: (2018)

Poly(ethylene glycol)-poly(ε-caprolactone)-based micelles for solubilization and tumor-targeted delivery of silibinin
por: Hassankhani Rad, Ashkan, et al.
Publicado: (2020)

Development of Self-Associating SN-38-Conjugated Poly(ethylene oxide)-Poly(ester) Micelles for Colorectal Cancer Therapy
por: Sadat, Sams M. A., et al.
Publicado: (2020)

Three-Dimensional Reconstructed Bone Marrow Matrix Culture Improves the Viability of Primary Myeloma Cells In-Vitro via a STAT3-Dependent Mechanism
por: Huang, Yung-Hsing, et al.
Publicado: (2021)

Development of Traceable Rituximab-Modified PEO-Polyester Micelles by Postinsertion of PEG-phospholipids for Targeting of B-cell Lymphoma
por: Saqr, Asma, et al.
Publicado: (2019)

The clinical and biological significance of STAT1 in esophageal squamous cell carcinoma
por: Zhang, Ying, et al.
Publicado: (2014)

Modulation of Hypoxia-Induced Chemoresistance to Polymeric Micellar Cisplatin: The Effect of Ligand Modification of Micellar Carrier Versus Inhibition of the Mediators of Drug Resistance
por: Soleymani Abyaneh, Hoda, et al.
Publicado: (2018)

Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands
por: Rostamizadeh, Leila, et al.
Publicado: (2022)

Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis
por: de Paiva, Igor Moura, et al.
Publicado: (2022)

Polymeric Micelles for Apoptosis-Targeted Optical Imaging of Cancer and Intraoperative Surgical Guidance
por: Cho, Hyunah, et al.
Publicado: (2014)

Shedding Light on the Elephant in a Dark Room in the Discovery of New Medicine: Highlighting Molecular Pharmaceutics within ACS Bio & Med Chem Au
por: Lavasanifar, Afsaneh, et al.
Publicado: (2022)

Combined Treatment with Stattic and Docetaxel Alters the Bax/Bcl-2 Gene Expression Ratio in Human Prostate Cancer Cells
por: Mohammadian, Jamal, et al.
Publicado: (2016)

Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds
por: Amiri, Mina, et al.
Publicado: (2023)

Developing a high-performance liquid chromatography fast and accurate method for quantification of silibinin
por: Bakhshi, Faezeh, et al.
Publicado: (2019)

Evaluation of anti-proliferative activity of Eryngium caucasicum on melanoma cancer cells
por: Forouhandeh, Haleh, et al.
Publicado: (2022)

Silibinin induces immunogenic cell death in cancer cells and enhances the induced immunogenicity by chemotherapy
por: Jafari, Sevda, et al.
Publicado: (2023)

STAT3 but Not HIF-1α Is Important in Mediating Hypoxia-Induced Chemoresistance in MDA-MB-231, a Triple Negative Breast Cancer Cell Line
por: Soleymani Abyaneh, Hoda, et al.
Publicado: (2017)

Clinical Significance of Carnitine in the Treatment of Cancer: From Traffic to the Regulation
por: Farahzadi, Raheleh, et al.
Publicado: (2023)

Nitrogen-doped amorphous carbon-silicon core-shell structures for high-power supercapacitor electrodes
por: Tali, S. A. Safiabadi, et al.
Publicado: (2017)

Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
por: Farahzadi, Raheleh, et al.
Publicado: (2023)

Elevated mitochondrial activity distinguishes fibrogenic hepatic stellate cells and sensitizes for selective inhibition by mitotropic doxorubicin
por: Gajendiran, Priya, et al.
Publicado: (2018)

Welcome to ACS Bio & Med Chem Au
por: Booker, Squire J., et al.
Publicado: (2021)

Performance of Impregnated Paper Decorated Blockboard Manufactured Using HDF as Equilibrium Layer
por: Fang, Lu, et al.
Publicado: (2022)

Nano-Delivery of a Novel Inhibitor of Polynucleotide Kinase/Phosphatase (PNKP) for Targeted Sensitization of Colorectal Cancer to Radiation-Induced DNA Damage
por: Sadat, Sams M. A., et al.
Publicado: (2021)

Silibinin sensitizes chemo-resistant breast cancer cells to chemotherapy
por: Molavi, Ommoleila, et al.
Publicado: (2016)

The Anti-CD38 Antibody Therapy in Multiple Myeloma
por: Petrucci, Maria Teresa, et al.
Publicado: (2019)

CD38-Directed Therapies for Management of Multiple Myeloma
por: Hashmi, Hamza, et al.
Publicado: (2021)

Development of a RP-HPLC method for analysis of docetaxel in tumor-bearing mice plasma and tissues following injection of docetaxel-loaded pH responsive targeting polymeric micelles
por: Kazemi, Moloud, et al.
Publicado: (2020)

Controversy in the Use of CD38 Antibody for Treatment of Myeloma: Is High CD38 Expression Good or Bad?
por: Plesner, Torben, et al.
Publicado: (2020)

CD38: A Target for Immunotherapeutic Approaches in Multiple Myeloma
por: Morandi, Fabio, et al.
Publicado: (2018)

Mechanisms of Resistance to Anti-CD38 Daratumumab in Multiple Myeloma
por: Saltarella, Ilaria, et al.
Publicado: (2020)

Anti CD38 monoclonal antibodies for multiple myeloma treatment
por: Gozzetti, Alessandro, et al.
Publicado: (2022)

Decoration = Decoración = Décoration = Dekoration /
por: Haro Lebrija, Fernando de
Publicado: (2007)

Decoration = Decoración = Décoration = Dekoration
por: Haro Lebrija, Fernando de
Publicado: (2011)

Decoration = Decoración = Décoration = Dekoration /
por: Haro Lebrija, Fernando de
Publicado: (2012)

EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma
por: Chemlal, Djamila, et al.
Publicado: (2023)

Medical education reform: a catalyst for strengthening the health system. Are we ready, Canada?
por: Sanaee, Layli
Publicado: (2019)

CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance
por: van de Donk, Niels W.C.J., et al.
Publicado: (2018)

Regulation of CD38 on Multiple Myeloma and NK Cells by Monoclonal Antibodies
por: Wu, Hao-Tian, et al.
Publicado: (2022)

Novel Insights in Anti-CD38 Therapy Based on CD38-Receptor Expression and Function: The Multiple Myeloma Model
por: Zannetti, Beatrice Anna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2daf5lj8j7h5c5mj1jkladv4lc