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Origin of mutations in genes associated with human glioblastoma multiform cancer: random polymerase errors versus deamination
The etiology of glioblastoma multiforme (GBM), the most serious form of brain cancer, remains obscure, although it has been proposed that cancer risk is a function of random polymerase errors that occur during stem cell division and the resulting mutations in oncogenes and tumor suppressor genes. An...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407082/ https://www.ncbi.nlm.nih.gov/pubmed/30899826 http://dx.doi.org/10.1016/j.heliyon.2019.e01265 |