Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome

BACKGROUND: Transposable elements make up a significant portion of the human genome. Accurately locating these mobile DNAs is vital to understand their role as a source of structural variation and somatic mutation. To this end, laboratories have developed strategies to selectively amplify or otherwi...

Descripción completa

Detalles Bibliográficos
Autores principales: Steranka, Jared P., Tang, Zuojian, Grivainis, Mark, Huang, Cheng Ran Lisa, Payer, Lindsay M., Rego, Fernanda O. R., Miller, Thiago Luiz Araujo, Galante, Pedro A. F., Ramaswami, Sitharam, Heguy, Adriana, Fenyö, David, Boeke, Jef D., Burns, Kathleen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407172/
https://www.ncbi.nlm.nih.gov/pubmed/30899333
http://dx.doi.org/10.1186/s13100-019-0148-5

Ejemplares similares

Ejemplares similares