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Rare cause of Hemophagocytic Lymphohistiocytosis due to mutation in PRF1 and SH2D1A genes in two children – a case report with a review

BACKGROUND: Hemophagocytic Lymphohistiocytosis (HLH) is a rare, complex, life-threatening hyper-inflammatory condition due to over activation of lymphocytes mediated secretory cytokines in the body. It occurs as a primary HLH due to genetic defect that mostly occurs in the childhood and associated w...

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Detalles Bibliográficos
Autores principales:	Sheth, Jayesh, Patel, Akash, Shah, Raju, Bhavsar, Riddhi, Trivedi, Sunil, Sheth, Frenny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407181/ https://www.ncbi.nlm.nih.gov/pubmed/30849948 http://dx.doi.org/10.1186/s12887-019-1444-4

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