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Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion

BACKGROUND: Cyclin-dependent kinase-like 1 (CDKL1) is a member of the cell division control protein 2-related serine–threonine protein kinase family. It is known to occur in various malignant tumors, but its role in neuroblastoma (NB) remains unclear. METHODS: We constructed a CDKL1-silenced NB cell...

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Detalles Bibliográficos
Autores principales: Li, Weiyi, Cao, Jing, Liu, Jian, Chu, Wenli, Zhang, Congqing, Chen, Shuiling, Kang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407201/
https://www.ncbi.nlm.nih.gov/pubmed/30891073
http://dx.doi.org/10.1186/s11658-019-0139-z