Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial

BACKGROUND: Fever improves pathogen control at a significant metabolic cost. No randomized clinical trials (RCT) have compared fever treatment thresholds in critically ill children. We performed a pilot RCT to determine whether a definitive trial of a permissive approach to fever in comparison to cu...

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Detalles Bibliográficos
Autores principales: Peters, Mark J., Woolfall, Kerry, Khan, Imran, Deja, Elisabeth, Mouncey, Paul R., Wulff, Jerome, Mason, Alexina, Agbeko, Rachel S., Draper, Elizabeth S., Fenn, Blaise, Gould, Doug W., Koelewyn, Abby, Klein, Nigel, Mackerness, Christine, Martin, Sian, O’Neill, Lauran, Ray, Samiran, Ramnarayan, Padmanabhan, Tibby, Shane, Thorburn, Kentigern, Tume, Lyvonne, Watkins, Jason, Wellman, Paul, Harrison, David A., Rowan, Kathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407208/
https://www.ncbi.nlm.nih.gov/pubmed/30845977
http://dx.doi.org/10.1186/s13054-019-2354-4

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