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Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures

BACKGROUND: Right ventricle (RV) size and function assessment by echocardiography (echo) is a standard tool in the ICU. Frequently subjective assessment is performed, and guidelines suggest its utility in adequately trained clinicians. We aimed to compare subjective (visual) assessment of RV size an...

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Autores principales: Orde, Sam, Slama, Michel, Yastrebov, Konstantin, Mclean, Anthony, Huang, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407213/
https://www.ncbi.nlm.nih.gov/pubmed/30845976
http://dx.doi.org/10.1186/s13054-019-2375-z
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author Orde, Sam
Slama, Michel
Yastrebov, Konstantin
Mclean, Anthony
Huang, Stephen
author_facet Orde, Sam
Slama, Michel
Yastrebov, Konstantin
Mclean, Anthony
Huang, Stephen
author_sort Orde, Sam
collection PubMed
description BACKGROUND: Right ventricle (RV) size and function assessment by echocardiography (echo) is a standard tool in the ICU. Frequently subjective assessment is performed, and guidelines suggest its utility in adequately trained clinicians. We aimed to compare subjective (visual) assessment of RV size and function by ICU physicians, with advanced qualifications in echocardiography, vs objective measurements. METHODS: ICU specialists with a qualification in advanced echocardiography reviewed 2D echo clips from critically ill patients on mechanical ventilation with PaO(2):FiO(2) < 300. Subjective assessments of RV size and function were made independently using a three-class categorical scale. Agreement (B-score) and bias (p value) were analysed using objective echo measurements. RV size assessment included RV end-diastolic area (EDA) and diameters. RV function assessment included fractional area change, S′, TAPSE and RV free wall strain. Binary and ordinal analysis was performed. RESULTS: Fifty-two clinicians reviewed 2D images from 80 patients. Fair agreement was seen with objective measures vs binary assessment of RV size (RV EDA 0.26 [p < 0.001], RV dimensions 0.29 [p = 0.06]) and function (RV free wall strain 0.27 [p < 0.001], TAPSE 0.27 [p < 0.001], S′ 0.29 [p < 0.001], FAC 0.31 [p = 0.16]). However, ordinal data analysis showed poor agreement with RV dimensions (0.11 [p = 0.06]) and RV free wall strain (0.14 [p = 0.16]). If one-step disagreement was allowed, agreement was good (RV dimensions 0.6 [p = 0.06], RV free wall strain 0.6 [p = 0.16]). Significant overestimation of severity of abnormalities was seen with subjective assessment vs RV EDA, TAPSE, S′ and fractional area change. CONCLUSION: Subjective (visual) assessment of RV size and function, by ICU specialists trained in advanced echo, can be fairly reliable for the initial exclusion of significant RV pathology. It seems prudent to avoid subjective RV assessment in isolation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13054-019-2375-z) contains supplementary material, which is available to authorized users.
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spelling pubmed-64072132019-03-21 Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures Orde, Sam Slama, Michel Yastrebov, Konstantin Mclean, Anthony Huang, Stephen Crit Care Research BACKGROUND: Right ventricle (RV) size and function assessment by echocardiography (echo) is a standard tool in the ICU. Frequently subjective assessment is performed, and guidelines suggest its utility in adequately trained clinicians. We aimed to compare subjective (visual) assessment of RV size and function by ICU physicians, with advanced qualifications in echocardiography, vs objective measurements. METHODS: ICU specialists with a qualification in advanced echocardiography reviewed 2D echo clips from critically ill patients on mechanical ventilation with PaO(2):FiO(2) < 300. Subjective assessments of RV size and function were made independently using a three-class categorical scale. Agreement (B-score) and bias (p value) were analysed using objective echo measurements. RV size assessment included RV end-diastolic area (EDA) and diameters. RV function assessment included fractional area change, S′, TAPSE and RV free wall strain. Binary and ordinal analysis was performed. RESULTS: Fifty-two clinicians reviewed 2D images from 80 patients. Fair agreement was seen with objective measures vs binary assessment of RV size (RV EDA 0.26 [p < 0.001], RV dimensions 0.29 [p = 0.06]) and function (RV free wall strain 0.27 [p < 0.001], TAPSE 0.27 [p < 0.001], S′ 0.29 [p < 0.001], FAC 0.31 [p = 0.16]). However, ordinal data analysis showed poor agreement with RV dimensions (0.11 [p = 0.06]) and RV free wall strain (0.14 [p = 0.16]). If one-step disagreement was allowed, agreement was good (RV dimensions 0.6 [p = 0.06], RV free wall strain 0.6 [p = 0.16]). Significant overestimation of severity of abnormalities was seen with subjective assessment vs RV EDA, TAPSE, S′ and fractional area change. CONCLUSION: Subjective (visual) assessment of RV size and function, by ICU specialists trained in advanced echo, can be fairly reliable for the initial exclusion of significant RV pathology. It seems prudent to avoid subjective RV assessment in isolation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13054-019-2375-z) contains supplementary material, which is available to authorized users. BioMed Central 2019-03-07 /pmc/articles/PMC6407213/ /pubmed/30845976 http://dx.doi.org/10.1186/s13054-019-2375-z Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Orde, Sam
Slama, Michel
Yastrebov, Konstantin
Mclean, Anthony
Huang, Stephen
Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
title Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
title_full Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
title_fullStr Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
title_full_unstemmed Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
title_short Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
title_sort subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407213/
https://www.ncbi.nlm.nih.gov/pubmed/30845976
http://dx.doi.org/10.1186/s13054-019-2375-z
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