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How should we treat uncomplicated subacute type B aortic dissection in octogenarians?
BACKGROUND: Preemptive thoracic endovascular aortic repair (TEVAR) is an advanced treatment that has possibility to improve late outcomes in patients with subacute type B aortic dissection. However, it may not be the treatment of choice for elderly patients with uncomplicated subacute type B aortic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407218/ https://www.ncbi.nlm.nih.gov/pubmed/30845982 http://dx.doi.org/10.1186/s13019-019-0869-z |
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author | Nakamura, Ken Uchida, Tetsuro Hamasaki, Azumi Sadahiro, Mitsuaki |
author_facet | Nakamura, Ken Uchida, Tetsuro Hamasaki, Azumi Sadahiro, Mitsuaki |
author_sort | Nakamura, Ken |
collection | PubMed |
description | BACKGROUND: Preemptive thoracic endovascular aortic repair (TEVAR) is an advanced treatment that has possibility to improve late outcomes in patients with subacute type B aortic dissection. However, it may not be the treatment of choice for elderly patients with uncomplicated subacute type B aortic dissection because of their inherent frailty and increased risk of periprocedural complications. METHODS: Data were collected between July 2004 and October 2017 in Yamagata university hospital and between February 2016 and May 2018 in Nihonkai General hospital. A total of 152 medically treated subacute type B aortic dissection patients were enrolled in this study. Patients were divided into two groups: age 80 year and older group (Group O, n = 33, 22%) and a group < 80 years of age (Group U, n = 119, 78%). RESULTS: During follow-up, the incidence of adverse events was 27% (n = 9) in Group O and 37% (n = 44) in Group U (P = 0.409). The incidence of aortic rupture was 3% (n = 1), and the incidence of acute type A dissection was 3% (n = 1) in Group O. In Group O, only one patient (3%) died of aorto-bronchial fistula. The Group O patients had less surgical intervention (3 patients [9%] in Group O and 30 patients [25%] in Group U, P = 0.047), but aortic related death did not differ between the two groups. The 1-, 2-, and 5-year freedom from aorta-related death rates of Group O were 97, 97, and 97%, respectively, compared with 99, 94, and 91%, respectively, in Group U (P = 0.880). CONCLUSIONS: Patients aged 80 years and older who underwent medical treatment for acute and subacute type B dissection had excellent outcomes in chronic phase. The elderly patients had less surgical intervention, but aortic related death did not differ from younger patients. |
format | Online Article Text |
id | pubmed-6407218 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-64072182019-03-21 How should we treat uncomplicated subacute type B aortic dissection in octogenarians? Nakamura, Ken Uchida, Tetsuro Hamasaki, Azumi Sadahiro, Mitsuaki J Cardiothorac Surg Research Article BACKGROUND: Preemptive thoracic endovascular aortic repair (TEVAR) is an advanced treatment that has possibility to improve late outcomes in patients with subacute type B aortic dissection. However, it may not be the treatment of choice for elderly patients with uncomplicated subacute type B aortic dissection because of their inherent frailty and increased risk of periprocedural complications. METHODS: Data were collected between July 2004 and October 2017 in Yamagata university hospital and between February 2016 and May 2018 in Nihonkai General hospital. A total of 152 medically treated subacute type B aortic dissection patients were enrolled in this study. Patients were divided into two groups: age 80 year and older group (Group O, n = 33, 22%) and a group < 80 years of age (Group U, n = 119, 78%). RESULTS: During follow-up, the incidence of adverse events was 27% (n = 9) in Group O and 37% (n = 44) in Group U (P = 0.409). The incidence of aortic rupture was 3% (n = 1), and the incidence of acute type A dissection was 3% (n = 1) in Group O. In Group O, only one patient (3%) died of aorto-bronchial fistula. The Group O patients had less surgical intervention (3 patients [9%] in Group O and 30 patients [25%] in Group U, P = 0.047), but aortic related death did not differ between the two groups. The 1-, 2-, and 5-year freedom from aorta-related death rates of Group O were 97, 97, and 97%, respectively, compared with 99, 94, and 91%, respectively, in Group U (P = 0.880). CONCLUSIONS: Patients aged 80 years and older who underwent medical treatment for acute and subacute type B dissection had excellent outcomes in chronic phase. The elderly patients had less surgical intervention, but aortic related death did not differ from younger patients. BioMed Central 2019-02-26 /pmc/articles/PMC6407218/ /pubmed/30845982 http://dx.doi.org/10.1186/s13019-019-0869-z Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Nakamura, Ken Uchida, Tetsuro Hamasaki, Azumi Sadahiro, Mitsuaki How should we treat uncomplicated subacute type B aortic dissection in octogenarians? |
title | How should we treat uncomplicated subacute type B aortic dissection in octogenarians? |
title_full | How should we treat uncomplicated subacute type B aortic dissection in octogenarians? |
title_fullStr | How should we treat uncomplicated subacute type B aortic dissection in octogenarians? |
title_full_unstemmed | How should we treat uncomplicated subacute type B aortic dissection in octogenarians? |
title_short | How should we treat uncomplicated subacute type B aortic dissection in octogenarians? |
title_sort | how should we treat uncomplicated subacute type b aortic dissection in octogenarians? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407218/ https://www.ncbi.nlm.nih.gov/pubmed/30845982 http://dx.doi.org/10.1186/s13019-019-0869-z |
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