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Angiotensin II promotes ovarian cancer spheroid formation and metastasis by upregulation of lipid desaturation and suppression of endoplasmic reticulum stress

BACKGROUND: Angiotensin II (ANGII) and its receptor (AGTR1) have been proposed as significant contributors to metastasis in multiple cancers. Further, high AGTR1 levels are associated with poor epithelial ovarian cancer (EOC) outcomes. However, the mechanistic basis for these effects is unknown. Rec...

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Detalles Bibliográficos
Autores principales:	Zhang, Qingyu, Yu, Shan, Lam, Melody Man Ting, Poon, Terence Chuen Wai, Sun, Litao, Jiao, Yufei, Wong, Alice Sze Tsai, Lee, Leo Tsz On
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407256/ https://www.ncbi.nlm.nih.gov/pubmed/30845964 http://dx.doi.org/10.1186/s13046-019-1127-x

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