Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population

BACKGROUND: Airflow obstruction is a hallmark of chronic obstructive pulmonary disease (COPD), and is defined as either the ratio between forced expiratory volume in one second and forced vital capacity (FEV(1)/FVC) < 70% or < lower limit of normal (LLN). This study aimed to assess the overlap...

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Detalles Bibliográficos
Autores principales: van der Plaat, Diana A., Vonk, Judith M., Lahousse, Lies, de Jong, Kim, Faiz, Alen, Nedeljkovic, Ivana, Amin, Najaf, van Diemen, Cleo C., Brusselle, Guy G., Bossé, Yohan, Brandsma, Corry-Anke, Hao, Ke, Paré, Peter D., van Duijn, Cornelia M., Postma, Dirkje S., Boezen, H. Marike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407273/
https://www.ncbi.nlm.nih.gov/pubmed/30845926
http://dx.doi.org/10.1186/s12890-019-0811-0

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