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Automodified Poly(ADP-Ribose) Polymerase Analysisto Monitor DNA Damagein Peripheral Lymphocytes of Floriculturists Occupationally Exposed to Pesticides

Increased DNA damage and the propension to cancer development, depend on the modulation of the mechanisms to control and maintain genomic integrity. Poly(ADP-Ribose)Polymerase activation and automodification are early responses to genotoxic stress. Upon binding to DNA strand breaks, the enzyme, a mo...

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Detalles Bibliográficos
Autores principales: Imperato, Serena, Mistretta, Carmela, Marone, Maria, Migliaccio, Ilaria, Pulcinelli, Ilaria, Faraone Mennella, Maria Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407306/
https://www.ncbi.nlm.nih.gov/pubmed/30744056
http://dx.doi.org/10.3390/cells8020137