A single extra copy of Down syndrome critical region 1–4 results in impaired hepatic glucose homeostasis

OBJECTIVES: During fasting, hepatic gluconeogenesis is induced to maintain energy homeostasis. Moreover, abnormal dysregulation of hepatic glucose production is commonly observed in type 2 diabetes. However, the signaling components controlling hepatic glucose production to maintain normal glucose l...

Descripción completa

Detalles Bibliográficos
Autores principales: Seo, Dong Soo, Chau, Gia Cac, Baek, Kwan-Hyuck, Um, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407364/
https://www.ncbi.nlm.nih.gov/pubmed/30583978
http://dx.doi.org/10.1016/j.molmet.2018.12.002