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A single extra copy of Down syndrome critical region 1–4 results in impaired hepatic glucose homeostasis
OBJECTIVES: During fasting, hepatic gluconeogenesis is induced to maintain energy homeostasis. Moreover, abnormal dysregulation of hepatic glucose production is commonly observed in type 2 diabetes. However, the signaling components controlling hepatic glucose production to maintain normal glucose l...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407364/ https://www.ncbi.nlm.nih.gov/pubmed/30583978 http://dx.doi.org/10.1016/j.molmet.2018.12.002 |