GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice

OBJECTIVE: Analogues of GDF15 (Growth Differentiation Factor 15) are promising new anti-obesity therapies as pharmacological treatment with GDF15 results in dramatic reductions of food intake and body weight. GDF15 exerts its central anorexic effects by binding to the GFRAL receptor exclusively expr...

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Detalles Bibliográficos
Autores principales: Frikke-Schmidt, Henriette, Hultman, Karin, Galaske, Joseph W., Jørgensen, Sebastian B., Myers, Martin G., Seeley, Randy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407365/
https://www.ncbi.nlm.nih.gov/pubmed/30685336
http://dx.doi.org/10.1016/j.molmet.2019.01.003

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