Retinoblastoma discordance in families with twins

Retinoblastoma has an increased inheritance risk of germline RB1 mutations in offspring and siblings, especially twins. Three families, each having one retinoblastoma-affected twin, were selected for genetic analysis and DNA profiling. Germline RB1 mutations were found in all probands. DNA profiling...

Descripción completa

Detalles Bibliográficos
Autores principales: Abraham, Aloysius, Thirumalairaj, Kannan, Gaikwad, Namrata, Muthukkaruppan, Veerappan, Reddy, Alla G, Thangaraj, Kumarasamy, Kim, Usha, Vanniarajan, Ayyasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407382/
https://www.ncbi.nlm.nih.gov/pubmed/30777982
http://dx.doi.org/10.4103/ijo.IJO_1245_18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407382/
https://www.ncbi.nlm.nih.gov/pubmed/30777982
http://dx.doi.org/10.4103/ijo.IJO_1245_18

Ejemplares similares