Cargando…

A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats

Caprine pediculosis is an ectoparasitic disease of great concern among goat farmers in India. It may be caused by either sucking lice or chewing lice; the latter one results in severe skin lesions, leading to production loss. This study evaluated the effectiveness of the macrocytic lactone drug, ive...

Descripción completa

Detalles Bibliográficos
Autores principales: Ajith, Y., Dimri, Umesh, Gopalakrishnan, A., Devi, Gopinath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407458/
https://www.ncbi.nlm.nih.gov/pubmed/30843405
http://dx.doi.org/10.4102/ojvr.v86i1.1635
_version_ 1783401557152235520
author Ajith, Y.
Dimri, Umesh
Gopalakrishnan, A.
Devi, Gopinath
author_facet Ajith, Y.
Dimri, Umesh
Gopalakrishnan, A.
Devi, Gopinath
author_sort Ajith, Y.
collection PubMed
description Caprine pediculosis is an ectoparasitic disease of great concern among goat farmers in India. It may be caused by either sucking lice or chewing lice; the latter one results in severe skin lesions, leading to production loss. This study evaluated the effectiveness of the macrocytic lactone drug, ivermectin, administered via subcutaneous injection, against chewing lice Bovicola (Damalinia) caprae infestation in naturally infested goats. The study was conducted on 20 goats with severe B. caprae infestation. Animals of group A (n = 10) were treated using a single dose of ivermectin (200 µg/kg body weight) subcutaneously and animals of group B (n = 10) underwent placebo therapy using normal saline. The animals were examined on days 0, 3, 7, 14, 21, 28, 42 and 56 for lice counts. There was 100% elimination of lice in all animals of group A and effective protection from re-infection remained at least for 21 days. Considerable improvement in haematological parameters was also observed by day 21. Based on this study, ivermectin injected via a subcutaneous route can be used effectively for the therapeutic and prophylactic management of chewing lice infestation in goats maintained under an extensive grazing system.
format Online
Article
Text
id pubmed-6407458
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher AOSIS
record_format MEDLINE/PubMed
spelling pubmed-64074582019-03-14 A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats Ajith, Y. Dimri, Umesh Gopalakrishnan, A. Devi, Gopinath Onderstepoort J Vet Res Original Research Caprine pediculosis is an ectoparasitic disease of great concern among goat farmers in India. It may be caused by either sucking lice or chewing lice; the latter one results in severe skin lesions, leading to production loss. This study evaluated the effectiveness of the macrocytic lactone drug, ivermectin, administered via subcutaneous injection, against chewing lice Bovicola (Damalinia) caprae infestation in naturally infested goats. The study was conducted on 20 goats with severe B. caprae infestation. Animals of group A (n = 10) were treated using a single dose of ivermectin (200 µg/kg body weight) subcutaneously and animals of group B (n = 10) underwent placebo therapy using normal saline. The animals were examined on days 0, 3, 7, 14, 21, 28, 42 and 56 for lice counts. There was 100% elimination of lice in all animals of group A and effective protection from re-infection remained at least for 21 days. Considerable improvement in haematological parameters was also observed by day 21. Based on this study, ivermectin injected via a subcutaneous route can be used effectively for the therapeutic and prophylactic management of chewing lice infestation in goats maintained under an extensive grazing system. AOSIS 2019-01-30 /pmc/articles/PMC6407458/ /pubmed/30843405 http://dx.doi.org/10.4102/ojvr.v86i1.1635 Text en © 2019. The Authors https://creativecommons.org/licenses/by/4.0/ Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Original Research
Ajith, Y.
Dimri, Umesh
Gopalakrishnan, A.
Devi, Gopinath
A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats
title A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats
title_full A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats
title_fullStr A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats
title_full_unstemmed A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats
title_short A field study on the efficacy of ivermectin via subcutaneous route against chewing lice (Bovicola caprae) infestation in naturally infested goats
title_sort field study on the efficacy of ivermectin via subcutaneous route against chewing lice (bovicola caprae) infestation in naturally infested goats
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407458/
https://www.ncbi.nlm.nih.gov/pubmed/30843405
http://dx.doi.org/10.4102/ojvr.v86i1.1635
work_keys_str_mv AT ajithy afieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats
AT dimriumesh afieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats
AT gopalakrishnana afieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats
AT devigopinath afieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats
AT ajithy fieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats
AT dimriumesh fieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats
AT gopalakrishnana fieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats
AT devigopinath fieldstudyontheefficacyofivermectinviasubcutaneousrouteagainstchewinglicebovicolacapraeinfestationinnaturallyinfestedgoats