Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case

We report a 40-year-old woman who presented with multiple osteolytic bone lesions and hypercalcemia, which are rarely caused by chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Although receiving intensive chemotherapy and allogeneic transplantation, the patient had a poor outcome...

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Detalles Bibliográficos
Autores principales: Hua, Jian, Ide, Shiro, Ohara, Shin, Uchida, Tomoyuki, Inoue, Morihiro, Ohashi, Kazuteru, Hagihara, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JSLRT 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407471/
https://www.ncbi.nlm.nih.gov/pubmed/30416172
http://dx.doi.org/10.3960/jslrt.18023
Descripción
Sumario:We report a 40-year-old woman who presented with multiple osteolytic bone lesions and hypercalcemia, which are rarely caused by chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Although receiving intensive chemotherapy and allogeneic transplantation, the patient had a poor outcome with an overall survival of 2 years. To our knowledge, this presentation is extremely rare for B-chronic lymphocytic leukemia, and new treatment strategies may be needed for long-term control of the disease.

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