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Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case

We report a 40-year-old woman who presented with multiple osteolytic bone lesions and hypercalcemia, which are rarely caused by chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Although receiving intensive chemotherapy and allogeneic transplantation, the patient had a poor outcome...

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Autores principales: Hua, Jian, Ide, Shiro, Ohara, Shin, Uchida, Tomoyuki, Inoue, Morihiro, Ohashi, Kazuteru, Hagihara, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JSLRT 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407471/
https://www.ncbi.nlm.nih.gov/pubmed/30416172
http://dx.doi.org/10.3960/jslrt.18023
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author Hua, Jian
Ide, Shiro
Ohara, Shin
Uchida, Tomoyuki
Inoue, Morihiro
Ohashi, Kazuteru
Hagihara, Masao
author_facet Hua, Jian
Ide, Shiro
Ohara, Shin
Uchida, Tomoyuki
Inoue, Morihiro
Ohashi, Kazuteru
Hagihara, Masao
author_sort Hua, Jian
collection PubMed
description We report a 40-year-old woman who presented with multiple osteolytic bone lesions and hypercalcemia, which are rarely caused by chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Although receiving intensive chemotherapy and allogeneic transplantation, the patient had a poor outcome with an overall survival of 2 years. To our knowledge, this presentation is extremely rare for B-chronic lymphocytic leukemia, and new treatment strategies may be needed for long-term control of the disease.
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spelling pubmed-64074712019-05-29 Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case Hua, Jian Ide, Shiro Ohara, Shin Uchida, Tomoyuki Inoue, Morihiro Ohashi, Kazuteru Hagihara, Masao J Clin Exp Hematop Case Report We report a 40-year-old woman who presented with multiple osteolytic bone lesions and hypercalcemia, which are rarely caused by chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Although receiving intensive chemotherapy and allogeneic transplantation, the patient had a poor outcome with an overall survival of 2 years. To our knowledge, this presentation is extremely rare for B-chronic lymphocytic leukemia, and new treatment strategies may be needed for long-term control of the disease. JSLRT 2018-11-09 /pmc/articles/PMC6407471/ /pubmed/30416172 http://dx.doi.org/10.3960/jslrt.18023 Text en © 2018 by The Japanese Society for Lymphoreticular Tissue Research https://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution ShareAlike (CC BY-NC-SA) 4.0 License.
spellingShingle Case Report
Hua, Jian
Ide, Shiro
Ohara, Shin
Uchida, Tomoyuki
Inoue, Morihiro
Ohashi, Kazuteru
Hagihara, Masao
Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case
title Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case
title_full Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case
title_fullStr Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case
title_full_unstemmed Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case
title_short Hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case
title_sort hypercalcemia and osteolytic bone lesions as the major symptoms in a chronic lymphocytic leukemia/small lymphocytic lymphoma patient: a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407471/
https://www.ncbi.nlm.nih.gov/pubmed/30416172
http://dx.doi.org/10.3960/jslrt.18023
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