Cargando…
Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives
Some new 3H-quinazolin-4-one derivatives were synthesised and screened for anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities. Compound 15d was more potent in reducing the cell viabilities of HT-29 and SW620 cells lines to 38%, 36.7%, compared to 5-FU which demonstr...
Autores principales: | El-Sayed, Nahed N. E., Almaneai, Norah M., Ben Bacha, Abir, Al-Obeed, Omar, Ahmad, Rehan, Abdulla, Maha, Alafeefy, Ahmed M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407576/ https://www.ncbi.nlm.nih.gov/pubmed/30821525 http://dx.doi.org/10.1080/14756366.2019.1574780 |
Ejemplares similares
-
Synthesis, Antiphospholipase A(2), Antiprotease, Antibacterial Evaluation and Molecular Docking Analysis of Certain Novel Hydrazones
por: El-Sayed, Nahed N. E., et al.
Publicado: (2016) -
Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway
por: Al-Obeed, Omar, et al.
Publicado: (2018) -
Biological Evaluation, Molecular Docking Analyses,
and ADME Profiling of Certain New Quinazolinones as Anti-colorectal
Agents
por: El-Sayed, Nahed N. E., et al.
Publicado: (2022) -
Synthesis and Characterization of Some New Quinoxalin-2(1H)one and 2-Methyl-3H-quinazolin-4-one Derivatives Targeting the Onset and Progression of CRC with SAR, Molecular Docking, and ADMET Analyses
por: El-Sayed, Nahed N. E., et al.
Publicado: (2021) -
Antiproliferative and antimetabolic effects behind the anticancer property of fermented wheat germ extract
por: Otto, Christoph, et al.
Publicado: (2016)