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Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma

The relationship between promoter proximal transcription factor-associated gene expression and super-enhancer-driven transcriptional programs are not well defined. However, their distinct genomic occupancy suggests a mechanism for specific and separable gene control. We explored the transcriptional...

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Detalles Bibliográficos
Autores principales: Fulciniti, Mariateresa, Lin, Charles Y., Samur, Mehmet K., Lopez, Michael A., Singh, Irtisha, Lawlor, Matthew A., Szalat, Raphael E., Ott, Christopher J., Avet-Loiseau, Herve’, Anderson, Kenneth C., Young, Richard A., Bradner, James E., Munshi, Nikhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407615/
https://www.ncbi.nlm.nih.gov/pubmed/30590042
http://dx.doi.org/10.1016/j.celrep.2018.12.016