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POPX2 is a novel LATS phosphatase that regulates the Hippo pathway

The Hippo pathway regulates cell proliferation, survival, apoptosis and differentiation. During carcinogenesis, members of the Hippo pathway are mutated to avoid anoikis and promote anchorage independent growth. Although many regulators of the Hippo pathway have been reported, negative regulators of...

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Detalles Bibliográficos
Autores principales: Rahmat, Muhammad Bakhait, Zhang, Songjing, Koh, Cheng-Gee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407677/
https://www.ncbi.nlm.nih.gov/pubmed/30863499
http://dx.doi.org/10.18632/oncotarget.26689