Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak

Clinical and model studies indicate that low nitric oxide (NO) bioavailability due in part to profound hypoargininemia contributes to cerebral malaria (CM) pathogenesis. Protection against CM pathogenesis may be achieved by altering the diet before infection with Plasmodium falciparum infection (nut...

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Detalles Bibliográficos
Autores principales: Gramaglia, Irene, Velez, Joyce, Chang, Yu-Sun, Caparros-Wanderley, Wilson, Combes, Valery, Grau, Georges, Stins, Monique F., van der Heyde, Henri C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407779/
https://www.ncbi.nlm.nih.gov/pubmed/30849122
http://dx.doi.org/10.1371/journal.pone.0213428

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