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Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report

RATIONALE: Hepatocellular carcinoma (HCC) is the fifth most common cancer and third leading cause of cancer-related deaths worldwide. Nasopharyngeal metastasis of hepatocellular carcinoma is very rare. This is the first report of posttransplantation nasopharyngeal metastasis. PATIENT CONCERNS: A 45-...

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Autores principales: Lou, Li-Li, Zhang, Ying, Huang, Xu, Zhang, Li-Xia, Ji, Hui-Fan, Li, Xu, Guo, Xiao-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408045/
https://www.ncbi.nlm.nih.gov/pubmed/30762736
http://dx.doi.org/10.1097/MD.0000000000014368
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author Lou, Li-Li
Zhang, Ying
Huang, Xu
Zhang, Li-Xia
Ji, Hui-Fan
Li, Xu
Guo, Xiao-Lin
author_facet Lou, Li-Li
Zhang, Ying
Huang, Xu
Zhang, Li-Xia
Ji, Hui-Fan
Li, Xu
Guo, Xiao-Lin
author_sort Lou, Li-Li
collection PubMed
description RATIONALE: Hepatocellular carcinoma (HCC) is the fifth most common cancer and third leading cause of cancer-related deaths worldwide. Nasopharyngeal metastasis of hepatocellular carcinoma is very rare. This is the first report of posttransplantation nasopharyngeal metastasis. PATIENT CONCERNS: A 45-year-old man with a history of hepatitis B related hepatocellular carcinoma (HCC) in the right segment of the liver received an orthotopic liver transplant. Two year after the transplantation, he suffered from severe headache, and head contrast enhanced CT scans did not show clues for brain or skull metastasis. Then he developed hoarseness and dysphagia. DIAGNOSIS: The nasopharyngeal cancer was confirmed to be metastatic tumor from liver histologically according to biopsy. INTERVENTIONS: This patient underwent radiotherapy (RT) of the metastatic nasopharyngeal tumor, and there was significant symptomatic relief. OUTCOMES: The patient died 3 months after nasopharyngeal metastasis was diagnosed. LESSONS: Recurrence of hepatocellular carcinoma with metastasis of nasopharyngeal carcinoma after liver transplantation is rare, but the prognosis is very poor. Close follow-up of patients should be paid attention to prevent the occurrence of such diseases.
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spelling pubmed-64080452019-03-16 Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report Lou, Li-Li Zhang, Ying Huang, Xu Zhang, Li-Xia Ji, Hui-Fan Li, Xu Guo, Xiao-Lin Medicine (Baltimore) Research Article RATIONALE: Hepatocellular carcinoma (HCC) is the fifth most common cancer and third leading cause of cancer-related deaths worldwide. Nasopharyngeal metastasis of hepatocellular carcinoma is very rare. This is the first report of posttransplantation nasopharyngeal metastasis. PATIENT CONCERNS: A 45-year-old man with a history of hepatitis B related hepatocellular carcinoma (HCC) in the right segment of the liver received an orthotopic liver transplant. Two year after the transplantation, he suffered from severe headache, and head contrast enhanced CT scans did not show clues for brain or skull metastasis. Then he developed hoarseness and dysphagia. DIAGNOSIS: The nasopharyngeal cancer was confirmed to be metastatic tumor from liver histologically according to biopsy. INTERVENTIONS: This patient underwent radiotherapy (RT) of the metastatic nasopharyngeal tumor, and there was significant symptomatic relief. OUTCOMES: The patient died 3 months after nasopharyngeal metastasis was diagnosed. LESSONS: Recurrence of hepatocellular carcinoma with metastasis of nasopharyngeal carcinoma after liver transplantation is rare, but the prognosis is very poor. Close follow-up of patients should be paid attention to prevent the occurrence of such diseases. Wolters Kluwer Health 2019-02-15 /pmc/articles/PMC6408045/ /pubmed/30762736 http://dx.doi.org/10.1097/MD.0000000000014368 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Lou, Li-Li
Zhang, Ying
Huang, Xu
Zhang, Li-Xia
Ji, Hui-Fan
Li, Xu
Guo, Xiao-Lin
Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
title Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
title_full Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
title_fullStr Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
title_full_unstemmed Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
title_short Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
title_sort solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: a case report
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408045/
https://www.ncbi.nlm.nih.gov/pubmed/30762736
http://dx.doi.org/10.1097/MD.0000000000014368
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