Cargando…
Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
RATIONALE: Hepatocellular carcinoma (HCC) is the fifth most common cancer and third leading cause of cancer-related deaths worldwide. Nasopharyngeal metastasis of hepatocellular carcinoma is very rare. This is the first report of posttransplantation nasopharyngeal metastasis. PATIENT CONCERNS: A 45-...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408045/ https://www.ncbi.nlm.nih.gov/pubmed/30762736 http://dx.doi.org/10.1097/MD.0000000000014368 |
_version_ | 1783401688105746432 |
---|---|
author | Lou, Li-Li Zhang, Ying Huang, Xu Zhang, Li-Xia Ji, Hui-Fan Li, Xu Guo, Xiao-Lin |
author_facet | Lou, Li-Li Zhang, Ying Huang, Xu Zhang, Li-Xia Ji, Hui-Fan Li, Xu Guo, Xiao-Lin |
author_sort | Lou, Li-Li |
collection | PubMed |
description | RATIONALE: Hepatocellular carcinoma (HCC) is the fifth most common cancer and third leading cause of cancer-related deaths worldwide. Nasopharyngeal metastasis of hepatocellular carcinoma is very rare. This is the first report of posttransplantation nasopharyngeal metastasis. PATIENT CONCERNS: A 45-year-old man with a history of hepatitis B related hepatocellular carcinoma (HCC) in the right segment of the liver received an orthotopic liver transplant. Two year after the transplantation, he suffered from severe headache, and head contrast enhanced CT scans did not show clues for brain or skull metastasis. Then he developed hoarseness and dysphagia. DIAGNOSIS: The nasopharyngeal cancer was confirmed to be metastatic tumor from liver histologically according to biopsy. INTERVENTIONS: This patient underwent radiotherapy (RT) of the metastatic nasopharyngeal tumor, and there was significant symptomatic relief. OUTCOMES: The patient died 3 months after nasopharyngeal metastasis was diagnosed. LESSONS: Recurrence of hepatocellular carcinoma with metastasis of nasopharyngeal carcinoma after liver transplantation is rare, but the prognosis is very poor. Close follow-up of patients should be paid attention to prevent the occurrence of such diseases. |
format | Online Article Text |
id | pubmed-6408045 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-64080452019-03-16 Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report Lou, Li-Li Zhang, Ying Huang, Xu Zhang, Li-Xia Ji, Hui-Fan Li, Xu Guo, Xiao-Lin Medicine (Baltimore) Research Article RATIONALE: Hepatocellular carcinoma (HCC) is the fifth most common cancer and third leading cause of cancer-related deaths worldwide. Nasopharyngeal metastasis of hepatocellular carcinoma is very rare. This is the first report of posttransplantation nasopharyngeal metastasis. PATIENT CONCERNS: A 45-year-old man with a history of hepatitis B related hepatocellular carcinoma (HCC) in the right segment of the liver received an orthotopic liver transplant. Two year after the transplantation, he suffered from severe headache, and head contrast enhanced CT scans did not show clues for brain or skull metastasis. Then he developed hoarseness and dysphagia. DIAGNOSIS: The nasopharyngeal cancer was confirmed to be metastatic tumor from liver histologically according to biopsy. INTERVENTIONS: This patient underwent radiotherapy (RT) of the metastatic nasopharyngeal tumor, and there was significant symptomatic relief. OUTCOMES: The patient died 3 months after nasopharyngeal metastasis was diagnosed. LESSONS: Recurrence of hepatocellular carcinoma with metastasis of nasopharyngeal carcinoma after liver transplantation is rare, but the prognosis is very poor. Close follow-up of patients should be paid attention to prevent the occurrence of such diseases. Wolters Kluwer Health 2019-02-15 /pmc/articles/PMC6408045/ /pubmed/30762736 http://dx.doi.org/10.1097/MD.0000000000014368 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Lou, Li-Li Zhang, Ying Huang, Xu Zhang, Li-Xia Ji, Hui-Fan Li, Xu Guo, Xiao-Lin Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report |
title | Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report |
title_full | Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report |
title_fullStr | Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report |
title_full_unstemmed | Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report |
title_short | Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report |
title_sort | solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: a case report |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408045/ https://www.ncbi.nlm.nih.gov/pubmed/30762736 http://dx.doi.org/10.1097/MD.0000000000014368 |
work_keys_str_mv | AT loulili solitarynasopharynxmetastasisfromhepatocellularcarcinomaafterlivertransplantationacasereport AT zhangying solitarynasopharynxmetastasisfromhepatocellularcarcinomaafterlivertransplantationacasereport AT huangxu solitarynasopharynxmetastasisfromhepatocellularcarcinomaafterlivertransplantationacasereport AT zhanglixia solitarynasopharynxmetastasisfromhepatocellularcarcinomaafterlivertransplantationacasereport AT jihuifan solitarynasopharynxmetastasisfromhepatocellularcarcinomaafterlivertransplantationacasereport AT lixu solitarynasopharynxmetastasisfromhepatocellularcarcinomaafterlivertransplantationacasereport AT guoxiaolin solitarynasopharynxmetastasisfromhepatocellularcarcinomaafterlivertransplantationacasereport |