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A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction

RATIONALE: We report a rare case of a pregnant woman with placental mesenchymal dysplasia (PMD) and intrauterine growth restriction (IUGR) with a genetically normal fetus. PATIENT CONCERNS: A 42-year-old woman Gravida I, Para I with pre-existent uncontrolled hypertension and uterine polyfibromatosis...

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Autores principales: Doroftei, Bogdan, Neculai-Valeanu, Sabina, Simionescu, Gabriela, Grab, Delia, Plopa, Natalia, Anton, Emil, Maftei, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408077/
https://www.ncbi.nlm.nih.gov/pubmed/30813167
http://dx.doi.org/10.1097/MD.0000000000014554
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author Doroftei, Bogdan
Neculai-Valeanu, Sabina
Simionescu, Gabriela
Grab, Delia
Plopa, Natalia
Anton, Emil
Maftei, Radu
author_facet Doroftei, Bogdan
Neculai-Valeanu, Sabina
Simionescu, Gabriela
Grab, Delia
Plopa, Natalia
Anton, Emil
Maftei, Radu
author_sort Doroftei, Bogdan
collection PubMed
description RATIONALE: We report a rare case of a pregnant woman with placental mesenchymal dysplasia (PMD) and intrauterine growth restriction (IUGR) with a genetically normal fetus. PATIENT CONCERNS: A 42-year-old woman Gravida I, Para I with pre-existent uncontrolled hypertension and uterine polyfibromatosis present at 30 weeks of gestation for diminished fetal activity during the last 2 days. DIAGNOSIS: Placental mesenchymal dysplasia associated with intrauterine growth restriction, hypertension, and uterine polyfibromatosis. INTERVENTION: A live male infant was delivered by emergency caesarean section. OUTCOMES: The infant, weighing 700 g, died 4 days after birth due to a massive intracerebral hemorrhage. LESSONS: A careful examination should be done at every ultrasound in case of a fetus with IUGR to exclude some rare cases of placental pathologies. PMD can be a rare cause of IUGR with a genetically normal fetus.
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spelling pubmed-64080772019-03-16 A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction Doroftei, Bogdan Neculai-Valeanu, Sabina Simionescu, Gabriela Grab, Delia Plopa, Natalia Anton, Emil Maftei, Radu Medicine (Baltimore) Research Article RATIONALE: We report a rare case of a pregnant woman with placental mesenchymal dysplasia (PMD) and intrauterine growth restriction (IUGR) with a genetically normal fetus. PATIENT CONCERNS: A 42-year-old woman Gravida I, Para I with pre-existent uncontrolled hypertension and uterine polyfibromatosis present at 30 weeks of gestation for diminished fetal activity during the last 2 days. DIAGNOSIS: Placental mesenchymal dysplasia associated with intrauterine growth restriction, hypertension, and uterine polyfibromatosis. INTERVENTION: A live male infant was delivered by emergency caesarean section. OUTCOMES: The infant, weighing 700 g, died 4 days after birth due to a massive intracerebral hemorrhage. LESSONS: A careful examination should be done at every ultrasound in case of a fetus with IUGR to exclude some rare cases of placental pathologies. PMD can be a rare cause of IUGR with a genetically normal fetus. Wolters Kluwer Health 2019-02-22 /pmc/articles/PMC6408077/ /pubmed/30813167 http://dx.doi.org/10.1097/MD.0000000000014554 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle Research Article
Doroftei, Bogdan
Neculai-Valeanu, Sabina
Simionescu, Gabriela
Grab, Delia
Plopa, Natalia
Anton, Emil
Maftei, Radu
A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction
title A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction
title_full A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction
title_fullStr A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction
title_full_unstemmed A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction
title_short A case report of placental mesenchymal dysplasia: A rare case of a genetically normal fetus with severe intrauterine growth restriction
title_sort case report of placental mesenchymal dysplasia: a rare case of a genetically normal fetus with severe intrauterine growth restriction
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408077/
https://www.ncbi.nlm.nih.gov/pubmed/30813167
http://dx.doi.org/10.1097/MD.0000000000014554
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