Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers

The liver plays a central role in metabolism; however, xenobiotic metabolism variations between human hepatocytes and those in model organisms create challenges in establishing functional test beds to detect the potential drug toxicity and efficacy of candidate small molecules. In the emerging areas...

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Detalles Bibliográficos
Autores principales: Mancio-Silva, Liliana, Fleming, Heather E., Miller, Alex B., Milstein, Stuart, Liebow, Abigail, Haslett, Patrick, Sepp-Lorenzino, Laura, Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408324/
https://www.ncbi.nlm.nih.gov/pubmed/30840913
http://dx.doi.org/10.1016/j.cmet.2019.02.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408324/
https://www.ncbi.nlm.nih.gov/pubmed/30840913
http://dx.doi.org/10.1016/j.cmet.2019.02.003

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