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Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae
Evolutionarily conserved virulence factors can be candidate therapeutic targets or vaccine antigens. Here, we investigated the evolutionary selective pressures on 16 pneumococcal choline-binding cell-surface proteins since Streptococcus pneumoniae is one of the pathogens posing the greatest threats...
Autores principales: | Yamaguchi, Masaya, Goto, Kana, Hirose, Yujiro, Yamaguchi, Yuka, Sumitomo, Tomoko, Nakata, Masanobu, Nakano, Kazuhiko, Kawabata, Shigetada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408437/ https://www.ncbi.nlm.nih.gov/pubmed/30886906 http://dx.doi.org/10.1038/s42003-019-0340-7 |
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