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Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

Evolutionarily conserved virulence factors can be candidate therapeutic targets or vaccine antigens. Here, we investigated the evolutionary selective pressures on 16 pneumococcal choline-binding cell-surface proteins since Streptococcus pneumoniae is one of the pathogens posing the greatest threats...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Masaya, Goto, Kana, Hirose, Yujiro, Yamaguchi, Yuka, Sumitomo, Tomoko, Nakata, Masanobu, Nakano, Kazuhiko, Kawabata, Shigetada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408437/
https://www.ncbi.nlm.nih.gov/pubmed/30886906
http://dx.doi.org/10.1038/s42003-019-0340-7

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