A Ca(2+)-regulated deAMPylation switch in human and bacterial FIC proteins

FIC proteins regulate molecular processes from bacteria to humans by catalyzing post-translational modifications (PTM), the most frequent being the addition of AMP or AMPylation. In many AMPylating FIC proteins, a structurally conserved glutamate represses AMPylation and, in mammalian FICD, also sup...

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Detalles Bibliográficos
Autores principales: Veyron, Simon, Oliva, Giulia, Rolando, Monica, Buchrieser, Carmen, Peyroche, Gérald, Cherfils, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408439/
https://www.ncbi.nlm.nih.gov/pubmed/30850593
http://dx.doi.org/10.1038/s41467-019-09023-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408439/
https://www.ncbi.nlm.nih.gov/pubmed/30850593
http://dx.doi.org/10.1038/s41467-019-09023-1

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