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A Ca(2+)-regulated deAMPylation switch in human and bacterial FIC proteins
FIC proteins regulate molecular processes from bacteria to humans by catalyzing post-translational modifications (PTM), the most frequent being the addition of AMP or AMPylation. In many AMPylating FIC proteins, a structurally conserved glutamate represses AMPylation and, in mammalian FICD, also sup...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408439/ https://www.ncbi.nlm.nih.gov/pubmed/30850593 http://dx.doi.org/10.1038/s41467-019-09023-1 |