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Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins

Conserved lipid transfer proteins of the Ups/PRELI family regulate lipid accumulation in mitochondria by shuttling phospholipids in a lipid-specific manner across the intermembrane space. Here, we combine structural analysis, unbiased genetic approaches in yeast and molecular dynamics simulations to...

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Detalles Bibliográficos
Autores principales:	Miliara, Xeni, Tatsuta, Takashi, Berry, Jamie-Lee, Rouse, Sarah L., Solak, Kübra, Chorev, Dror S., Wu, Di, Robinson, Carol V., Matthews, Stephen, Langer, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408443/ https://www.ncbi.nlm.nih.gov/pubmed/30850607 http://dx.doi.org/10.1038/s41467-019-09089-x

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