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Provisional Tic Disorder is not so transient

Motor and vocal tics are common in childhood. The received wisdom among clinicians is that for most children the tics are temporary, disappearing within a few months. However, that common clinical teaching is based largely on biased and incomplete data. The present study was designed to prospectivel...

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Autores principales: Kim, Soyoung, Greene, Deanna J., Bihun, Emily C., Koller, Jonathan M., Hampton, Jacqueline M., Acevedo, Haley, Reiersen, Angela M., Schlaggar, Bradley L., Black, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408476/
https://www.ncbi.nlm.nih.gov/pubmed/30850688
http://dx.doi.org/10.1038/s41598-019-40133-4
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author Kim, Soyoung
Greene, Deanna J.
Bihun, Emily C.
Koller, Jonathan M.
Hampton, Jacqueline M.
Acevedo, Haley
Reiersen, Angela M.
Schlaggar, Bradley L.
Black, Kevin J.
author_facet Kim, Soyoung
Greene, Deanna J.
Bihun, Emily C.
Koller, Jonathan M.
Hampton, Jacqueline M.
Acevedo, Haley
Reiersen, Angela M.
Schlaggar, Bradley L.
Black, Kevin J.
author_sort Kim, Soyoung
collection PubMed
description Motor and vocal tics are common in childhood. The received wisdom among clinicians is that for most children the tics are temporary, disappearing within a few months. However, that common clinical teaching is based largely on biased and incomplete data. The present study was designed to prospectively assess outcome of children with what the current nomenclature calls Provisional Tic Disorder. We identified 43 children with recent onset tics (mean 3.3 months since tic onset) and re-examined 39 of them on the 12-month anniversary of their first tic. Tic symptoms improved on a group level at the 12-month follow-up, and only two children had more than minimal impairment due to tics. Remarkably, however, tics were present in all children at follow-up, although in several cases tics were apparent only when the child was observed remotely by video. Our results suggest that remission of Provisional Tic Disorder is the exception rather than the rule. We also identified several clinical features present at the first examination that predict one-year outcome; these include baseline tic severity, subsyndromal autism spectrum symptoms, and the presence of an anxiety disorder.
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spelling pubmed-64084762019-03-12 Provisional Tic Disorder is not so transient Kim, Soyoung Greene, Deanna J. Bihun, Emily C. Koller, Jonathan M. Hampton, Jacqueline M. Acevedo, Haley Reiersen, Angela M. Schlaggar, Bradley L. Black, Kevin J. Sci Rep Article Motor and vocal tics are common in childhood. The received wisdom among clinicians is that for most children the tics are temporary, disappearing within a few months. However, that common clinical teaching is based largely on biased and incomplete data. The present study was designed to prospectively assess outcome of children with what the current nomenclature calls Provisional Tic Disorder. We identified 43 children with recent onset tics (mean 3.3 months since tic onset) and re-examined 39 of them on the 12-month anniversary of their first tic. Tic symptoms improved on a group level at the 12-month follow-up, and only two children had more than minimal impairment due to tics. Remarkably, however, tics were present in all children at follow-up, although in several cases tics were apparent only when the child was observed remotely by video. Our results suggest that remission of Provisional Tic Disorder is the exception rather than the rule. We also identified several clinical features present at the first examination that predict one-year outcome; these include baseline tic severity, subsyndromal autism spectrum symptoms, and the presence of an anxiety disorder. Nature Publishing Group UK 2019-03-08 /pmc/articles/PMC6408476/ /pubmed/30850688 http://dx.doi.org/10.1038/s41598-019-40133-4 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Kim, Soyoung
Greene, Deanna J.
Bihun, Emily C.
Koller, Jonathan M.
Hampton, Jacqueline M.
Acevedo, Haley
Reiersen, Angela M.
Schlaggar, Bradley L.
Black, Kevin J.
Provisional Tic Disorder is not so transient
title Provisional Tic Disorder is not so transient
title_full Provisional Tic Disorder is not so transient
title_fullStr Provisional Tic Disorder is not so transient
title_full_unstemmed Provisional Tic Disorder is not so transient
title_short Provisional Tic Disorder is not so transient
title_sort provisional tic disorder is not so transient
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408476/
https://www.ncbi.nlm.nih.gov/pubmed/30850688
http://dx.doi.org/10.1038/s41598-019-40133-4
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