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Early weaning increases anxiety via brain-derived neurotrophic factor signaling in the mouse prefrontal cortex
Deprivation of maternal care during early development markedly affects emotional development, but the underlying neuromolecular mechanisms are not fully understood. In a mouse model of disrupted mother-infant relationship, early weaning causes long-term impacts on pups to exhibit increased corticost...
Autores principales: | Kikusui, Takefumi, Kanbara, Natsumi, Ozaki, Mariya, Hirayama, Nozomi, Ida, Kumiko, Tokita, Mika, Tanabe, Naho, Mitsuyama, Kuriko, Abe, Hatsuki, Yoshida, Miki, Nagasawa, Miho, Mogi, Kazutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408497/ https://www.ncbi.nlm.nih.gov/pubmed/30850750 http://dx.doi.org/10.1038/s41598-019-40530-9 |
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