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Voluntary exercise in mice fed an obesogenic diet alters the hepatic immune phenotype and improves metabolic parameters – an animal model of life style intervention in NAFLD
Reproducible animal models to recapitulate the pathophysiology of non-alcoholic fatty liver disease (NAFLD) are urgently required to improve the understanding of the mechanisms of liver injury and to explore novel therapeutic options. Current guidelines recommend life-style interventions as first-li...
Autores principales: | Gehrke, Nadine, Biedenbach, Jana, Huber, Yvonne, Straub, Beate K., Galle, Peter R., Simon, Perikles, Schattenberg, Jörn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408519/ https://www.ncbi.nlm.nih.gov/pubmed/30850619 http://dx.doi.org/10.1038/s41598-018-38321-9 |
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