Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice

The morphogenesis of mammalian embryonic external genitalia (eExG) shows dynamic differences between males and females. In genotypic males, eExG are masculinized in response to androgen signaling. Disruption of this process can give rise to multiple male reproductive organ defects. Currently, mechan...

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Detalles Bibliográficos
Autores principales: Acebedo, Alvin R., Suzuki, Kentaro, Hino, Shinjiro, Alcantara, Mellissa C., Sato, Yuki, Haga, Hisashi, Matsumoto, Ken-ichi, Nakao, Mitsuyoshi, Shimamura, Kenji, Takeo, Toru, Nakagata, Naomi, Miyagawa, Shinichi, Nishinakamura, Ryuichi, Adelstein, Robert S., Yamada, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408527/
https://www.ncbi.nlm.nih.gov/pubmed/30886905
http://dx.doi.org/10.1038/s42003-019-0336-3

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