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Deep learning-based super-resolution in coherent imaging systems

We present a deep learning framework based on a generative adversarial network (GAN) to perform super-resolution in coherent imaging systems. We demonstrate that this framework can enhance the resolution of both pixel size-limited and diffraction-limited coherent imaging systems. The capabilities of...

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Detalles Bibliográficos
Autores principales: Liu, Tairan, de Haan, Kevin, Rivenson, Yair, Wei, Zhensong, Zeng, Xin, Zhang, Yibo, Ozcan, Aydogan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408569/
https://www.ncbi.nlm.nih.gov/pubmed/30850721
http://dx.doi.org/10.1038/s41598-019-40554-1
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author Liu, Tairan
de Haan, Kevin
Rivenson, Yair
Wei, Zhensong
Zeng, Xin
Zhang, Yibo
Ozcan, Aydogan
author_facet Liu, Tairan
de Haan, Kevin
Rivenson, Yair
Wei, Zhensong
Zeng, Xin
Zhang, Yibo
Ozcan, Aydogan
author_sort Liu, Tairan
collection PubMed
description We present a deep learning framework based on a generative adversarial network (GAN) to perform super-resolution in coherent imaging systems. We demonstrate that this framework can enhance the resolution of both pixel size-limited and diffraction-limited coherent imaging systems. The capabilities of this approach are experimentally validated by super-resolving complex-valued images acquired using a lensfree on-chip holographic microscope, the resolution of which was pixel size-limited. Using the same GAN-based approach, we also improved the resolution of a lens-based holographic imaging system that was limited in resolution by the numerical aperture of its objective lens. This deep learning-based super-resolution framework can be broadly applied to enhance the space-bandwidth product of coherent imaging systems using image data and convolutional neural networks, and provides a rapid, non-iterative method for solving inverse image reconstruction or enhancement problems in optics.
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spelling pubmed-64085692019-03-12 Deep learning-based super-resolution in coherent imaging systems Liu, Tairan de Haan, Kevin Rivenson, Yair Wei, Zhensong Zeng, Xin Zhang, Yibo Ozcan, Aydogan Sci Rep Article We present a deep learning framework based on a generative adversarial network (GAN) to perform super-resolution in coherent imaging systems. We demonstrate that this framework can enhance the resolution of both pixel size-limited and diffraction-limited coherent imaging systems. The capabilities of this approach are experimentally validated by super-resolving complex-valued images acquired using a lensfree on-chip holographic microscope, the resolution of which was pixel size-limited. Using the same GAN-based approach, we also improved the resolution of a lens-based holographic imaging system that was limited in resolution by the numerical aperture of its objective lens. This deep learning-based super-resolution framework can be broadly applied to enhance the space-bandwidth product of coherent imaging systems using image data and convolutional neural networks, and provides a rapid, non-iterative method for solving inverse image reconstruction or enhancement problems in optics. Nature Publishing Group UK 2019-03-08 /pmc/articles/PMC6408569/ /pubmed/30850721 http://dx.doi.org/10.1038/s41598-019-40554-1 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Liu, Tairan
de Haan, Kevin
Rivenson, Yair
Wei, Zhensong
Zeng, Xin
Zhang, Yibo
Ozcan, Aydogan
Deep learning-based super-resolution in coherent imaging systems
title Deep learning-based super-resolution in coherent imaging systems
title_full Deep learning-based super-resolution in coherent imaging systems
title_fullStr Deep learning-based super-resolution in coherent imaging systems
title_full_unstemmed Deep learning-based super-resolution in coherent imaging systems
title_short Deep learning-based super-resolution in coherent imaging systems
title_sort deep learning-based super-resolution in coherent imaging systems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408569/
https://www.ncbi.nlm.nih.gov/pubmed/30850721
http://dx.doi.org/10.1038/s41598-019-40554-1
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