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E-syt1 Re-arranges STIM1 Clusters to Stabilize Ring-shaped ER-PM Contact Sites and Accelerate Ca(2+) Store Replenishment

In many non-excitable cells, the depletion of endoplasmic reticulum (ER) Ca(2+) stores leads to the dynamic formation of membrane contact sites (MCSs) between the ER and the plasma membrane (PM), which activates the store-operated Ca(2+) entry (SOCE) to refill the ER store. Two different Ca(2+)-sens...

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Detalles Bibliográficos
Autores principales: Kang, Fei, Zhou, Mengxuan, Huang, Xiaoshuai, Fan, Junchao, Wei, Lisi, Boulanger, Jerome, Liu, Zengzhen, Salamero, Jean, Liu, Yanmei, Chen, Liangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408583/
https://www.ncbi.nlm.nih.gov/pubmed/30850711
http://dx.doi.org/10.1038/s41598-019-40331-0