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Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus
Tumor is a multifactorial sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyt...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408718/ https://www.ncbi.nlm.nih.gov/pubmed/30899178 http://dx.doi.org/10.1016/j.sjbs.2018.07.012 |
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author | Tuama, Ammar Adnan Mohammed, Arif Ahmed |
author_facet | Tuama, Ammar Adnan Mohammed, Arif Ahmed |
author_sort | Tuama, Ammar Adnan |
collection | PubMed |
description | Tumor is a multifactorial sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyto compounds profile of plant extracts and its effect on anticancer activity. Cucumber (Cucumis sativus L.) is a member of the Cucurbitaceae family like melon, squash and pumpkins. It is a popular vegetable harvest in Indian customary medicine since olden times. It has potential lipid lowering and antioxidant activity and antidiabetic. In the present study, we have evaluated the anticancer prospective of methanolic and acetone extracts of Cucumis sativus (CSME) and (CSAE). Reported results show that (CSME) is rich in bioactive compounds shown anticancer activity with Cell lines of (IC50) with MCF 715.6 ± 1.3 and HeLa 28.2 ± 1. This study on the presence of cytotoxic from the Cucumis sativus L.), which have been further used in herbal formulations study as an anticancer activity. Our conclusion support additional in-depth study of this pharmacologic activity as an malignant tumor agent. |
format | Online Article Text |
id | pubmed-6408718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-64087182019-03-21 Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus Tuama, Ammar Adnan Mohammed, Arif Ahmed Saudi J Biol Sci Article Tumor is a multifactorial sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyto compounds profile of plant extracts and its effect on anticancer activity. Cucumber (Cucumis sativus L.) is a member of the Cucurbitaceae family like melon, squash and pumpkins. It is a popular vegetable harvest in Indian customary medicine since olden times. It has potential lipid lowering and antioxidant activity and antidiabetic. In the present study, we have evaluated the anticancer prospective of methanolic and acetone extracts of Cucumis sativus (CSME) and (CSAE). Reported results show that (CSME) is rich in bioactive compounds shown anticancer activity with Cell lines of (IC50) with MCF 715.6 ± 1.3 and HeLa 28.2 ± 1. This study on the presence of cytotoxic from the Cucumis sativus L.), which have been further used in herbal formulations study as an anticancer activity. Our conclusion support additional in-depth study of this pharmacologic activity as an malignant tumor agent. Elsevier 2019-03 2018-07-31 /pmc/articles/PMC6408718/ /pubmed/30899178 http://dx.doi.org/10.1016/j.sjbs.2018.07.012 Text en © 2018 Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Tuama, Ammar Adnan Mohammed, Arif Ahmed Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus |
title | Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus |
title_full | Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus |
title_fullStr | Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus |
title_full_unstemmed | Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus |
title_short | Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus |
title_sort | phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of cucumis sativus |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408718/ https://www.ncbi.nlm.nih.gov/pubmed/30899178 http://dx.doi.org/10.1016/j.sjbs.2018.07.012 |
work_keys_str_mv | AT tuamaammaradnan phytochemicalscreeningandinvitroantibacterialandanticanceractivitiesoftheaqueousextractofcucumissativus AT mohammedarifahmed phytochemicalscreeningandinvitroantibacterialandanticanceractivitiesoftheaqueousextractofcucumissativus |