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Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus

Tumor is a multifactorial sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyt...

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Autores principales: Tuama, Ammar Adnan, Mohammed, Arif Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408718/
https://www.ncbi.nlm.nih.gov/pubmed/30899178
http://dx.doi.org/10.1016/j.sjbs.2018.07.012
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author Tuama, Ammar Adnan
Mohammed, Arif Ahmed
author_facet Tuama, Ammar Adnan
Mohammed, Arif Ahmed
author_sort Tuama, Ammar Adnan
collection PubMed
description Tumor is a multifactorial sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyto compounds profile of plant extracts and its effect on anticancer activity. Cucumber (Cucumis sativus L.) is a member of the Cucurbitaceae family like melon, squash and pumpkins. It is a popular vegetable harvest in Indian customary medicine since olden times. It has potential lipid lowering and antioxidant activity and antidiabetic. In the present study, we have evaluated the anticancer prospective of methanolic and acetone extracts of Cucumis sativus (CSME) and (CSAE). Reported results show that (CSME) is rich in bioactive compounds shown anticancer activity with Cell lines of (IC50) with MCF 715.6 ± 1.3 and HeLa 28.2 ± 1. This study on the presence of cytotoxic from the Cucumis sativus L.), which have been further used in herbal formulations study as an anticancer activity. Our conclusion support additional in-depth study of this pharmacologic activity as an malignant tumor agent.
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spelling pubmed-64087182019-03-21 Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus Tuama, Ammar Adnan Mohammed, Arif Ahmed Saudi J Biol Sci Article Tumor is a multifactorial sickness and consequently can be viably overwhelmed by a multi-constituently remedial strategy. Herbal extracts shows the example of such stratagem. However, less research have been carried out till date that portray the effect of different extraction techniques on the phyto compounds profile of plant extracts and its effect on anticancer activity. Cucumber (Cucumis sativus L.) is a member of the Cucurbitaceae family like melon, squash and pumpkins. It is a popular vegetable harvest in Indian customary medicine since olden times. It has potential lipid lowering and antioxidant activity and antidiabetic. In the present study, we have evaluated the anticancer prospective of methanolic and acetone extracts of Cucumis sativus (CSME) and (CSAE). Reported results show that (CSME) is rich in bioactive compounds shown anticancer activity with Cell lines of (IC50) with MCF 715.6 ± 1.3 and HeLa 28.2 ± 1. This study on the presence of cytotoxic from the Cucumis sativus L.), which have been further used in herbal formulations study as an anticancer activity. Our conclusion support additional in-depth study of this pharmacologic activity as an malignant tumor agent. Elsevier 2019-03 2018-07-31 /pmc/articles/PMC6408718/ /pubmed/30899178 http://dx.doi.org/10.1016/j.sjbs.2018.07.012 Text en © 2018 Production and hosting by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Tuama, Ammar Adnan
Mohammed, Arif Ahmed
Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus
title Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus
title_full Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus
title_fullStr Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus
title_full_unstemmed Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus
title_short Phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of Cucumis sativus
title_sort phytochemical screening and in vitro antibacterial and anticancer activities of the aqueous extract of cucumis sativus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408718/
https://www.ncbi.nlm.nih.gov/pubmed/30899178
http://dx.doi.org/10.1016/j.sjbs.2018.07.012
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