Severe infections due to Francisella tularensis ssp. holarctica in solid organ transplant recipient: report of two cases and review of literature

BACKGROUND: Tularemia is a rare zoonotic infection caused by bacterium Francisella tularensis. It has been well described in immunocompetent patients but poorly described in immunocompromised patients notably in solid organ transplant recipients. CASE PRESENTATIONS: We report here two cases of tular...

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Detalles Bibliográficos
Autores principales: Bahuaud, Olivier, Le Brun, Cécile, Chalopin, Thomas, Lacasse, Marion, Le Marec, Julien, Pantaleon, Clémence, Nicolas, Charlotte, Barbier, Louise, Bernard, Louis, Lemaignen, Adrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408858/
https://www.ncbi.nlm.nih.gov/pubmed/30849949
http://dx.doi.org/10.1186/s12879-019-3863-0
Descripción
Sumario:BACKGROUND: Tularemia is a rare zoonotic infection caused by bacterium Francisella tularensis. It has been well described in immunocompetent patients but poorly described in immunocompromised patients notably in solid organ transplant recipients. CASE PRESENTATIONS: We report here two cases of tularemia in solid organ transplant recipients including first case after heart transplant. We also carried out an exhaustive review of literature describing characteristics of this infection in solid organ transplant recipients.

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