Cargando…
Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult
OBJECTIVE: Diabetic polyneuropathy (DPN) is one of the most prevalent diabetic complications. We previously demonstrated that exendin-4 (Ex4), a glucagon-like peptide-1 receptor agonist (GLP-1RA), has beneficial effects in animal models of DPN. We hypothesized that GLP-1 signaling would protect neur...
Autores principales: | Mohiuddin, Mohammad Sarif, Himeno, Tatsuhito, Inoue, Rieko, Miura-Yura, Emiri, Yamada, Yuichiro, Nakai-Shimoda, Hiromi, Asano, Saeko, Kato, Makoto, Motegi, Mikio, Kondo, Masaki, Seino, Yusuke, Tsunekawa, Shin, Kato, Yoshiro, Suzuki, Atsushi, Naruse, Keiko, Kato, Koichi, Nakamura, Jiro, Kamiya, Hideki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408997/ https://www.ncbi.nlm.nih.gov/pubmed/30918901 http://dx.doi.org/10.1155/2019/9426014 |
Ejemplares similares
-
Ranirestat Improved Nerve Conduction Velocities, Sensory Perception, and Intraepidermal Nerve Fiber Density in Rats with Overt Diabetic Polyneuropathy
por: Asano, Saeko, et al.
Publicado: (2019) -
Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin‐induced diabetic mice
por: Miura‐Yura, Emiri, et al.
Publicado: (2019) -
Protocol to image and analyze the morphology of mouse peripheral nerves using transmission electron microscopy
por: Nakai-Shimoda, Hiromi, et al.
Publicado: (2022) -
Glucagon Prevents Cytotoxicity Induced by Methylglyoxal in a Rat Neuronal Cell Line Model
por: Mohiuddin, Mohammad Sarif, et al.
Publicado: (2021) -
Thermal gradient ring reveals thermosensory changes in diabetic peripheral neuropathy in mice
por: Sasajima, Sachiko, et al.
Publicado: (2022)